Information on medical and demographic as well as sanitary-epidemiologic situation in town Verkhnyaya Pyshma is presented. The town belongs to group of territories with unfavourable ecologic situation. It was shown that social, economical, and sanitary-hygienic factors influence on public health. Priority pollutants of environment and indicators of public health are presented. For solving problems of protection of public health, ensuring the sanitary-epidemiologic welfare and ecologic safety in modern conditions, more effective, accessible, and economical mechanisms of management of environment and public health should be introduced with respect to action of factors of economical and social development of municipality as well as to realization of national projects.