Osseointegration of a subperiosteal anchoring device in the minipig mandible

Am J Orthod Dentofacial Orthop. 2008 May;133(5):743-7. doi: 10.1016/j.ajodo.2007.10.028.

Abstract

Introduction: Onplants serve as subperiosteal anchorage in the maxilla to facilitate tooth movement. We determined the applicability of onplants and the process of osseointegration in the mandible of minipigs.

Methods: Thirty-six onplants (OnPlants, Nobel Biocare USA, Yorba Linda, Calif) were positioned in 9 adult animals, 2 on each side. At 3, 6, and 12 weeks after surgery, 3 minipigs were killed. Undecalcified ground sections were evaluated histologically and histomorphometrically.

Results: Nineteen onplants were lost during the observation period. Newly formed bone per tissue volume was 7% +/- 5% (n = 4), 21% +/- 9% (n = 5), and 22% +/- 13% (n = 8) at the 3 observation times. The corresponding percentages of bone-to-implant contact were 15% +/- 22%, 30% +/- 27%, and 44% +/- 35%. The number of bone-to-implant contacts remained stable over time at 1.0 +/- 0.9 contacts per millimeter. The average lengths of bone-to-implant contacts were 0.2 +/- 0.1 mm, 0.3 +/- 0.2 mm, and 0.5 +/- 0.3 mm.

Conclusions: These results showed a low survival rate of onplants in the mandible and that the early stage of healing is central to the process of osseointegration. Stable placement is a prerequisite for onplant survival in the mandible.

MeSH terms

  • Animals
  • Dental Implantation, Subperiosteal*
  • Female
  • Male
  • Mandible / surgery
  • Orthodontic Anchorage Procedures / instrumentation*
  • Osseointegration*
  • Swine
  • Swine, Miniature