Abstract
Chemical analysis of the fruiting bodies of the agaricoid fungus Cortinarius subtortus yielded three new natural products, two quinoline and one isocarbostyryl alkaloid. The structures of compounds 1- 3 were determined by analysis of NMR and MS data. Compound 1 exhibited inhibitory effects against the phytopathogenic fungus Colletotrichum coccodes. All three compounds displayed moderate antioxidant activity in a DPPH free radical scavenging bioassay.
MeSH terms
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Agaricales / chemistry*
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Alkaloids / chemistry
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Alkaloids / isolation & purification*
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Alkaloids / pharmacology
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Antifungal Agents / chemistry
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Antifungal Agents / isolation & purification*
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Antifungal Agents / pharmacology
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Antioxidants / chemistry
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Antioxidants / isolation & purification*
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Antioxidants / pharmacology
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Biphenyl Compounds
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Colletotrichum / drug effects*
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Colletotrichum / growth & development
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification*
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Free Radical Scavengers / pharmacology
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Fruiting Bodies, Fungal / chemistry
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Germany
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Isoquinolines / chemistry
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Isoquinolines / isolation & purification*
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Isoquinolines / pharmacology
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Picrates / pharmacology
Substances
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Alkaloids
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Antifungal Agents
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Antioxidants
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Biphenyl Compounds
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Free Radical Scavengers
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Isoquinolines
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Picrates
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1,1-diphenyl-2-picrylhydrazyl