Dinickel complexes of disubstituted benzoate polydentate ligands: mimics for the active site of urease

Dalton Trans. 2008 May 21:(19):2538-41. doi: 10.1039/b803094b. Epub 2008 Mar 28.

Abstract

Two dinickel mimics, [LNi2(DMF)4](ClO4)3 () and [L'Ni2(CH3CN)4](ClO4)3 (), for the active site of urease supported by a disubstituted benzoate polydentate ligand were synthesized and fully characterized, subsequently addition of urea afforded two urea adducts, [LNi2(urea)4](ClO4)3 () and [L'Ni2(urea)4](ClO4)3 ().

MeSH terms

  • Benzoates / chemistry*
  • Binding Sites
  • Ligands
  • Molecular Mimicry
  • Molecular Structure
  • Nickel / chemistry*
  • Organometallic Compounds / chemical synthesis*
  • Temperature
  • Urea / chemistry
  • Urease / chemistry
  • Urease / metabolism*

Substances

  • Benzoates
  • Ligands
  • Organometallic Compounds
  • Nickel
  • Urea
  • Urease