Genital herpes: gynaecological aspects

J Obstet Gynaecol Can. 2008 Apr;30(4):347-353. doi: 10.1016/S1701-2163(16)32805-5.
[Article in English, French]

Abstract

Objective: The purpose of this guideline is to provide recommendations to gynaecology health care providers on optimal management of genital herpes.

Outcomes: More effective prevention of complications and transmission of genital herpes.

Evidence: Medline was searched for articles published in French and English related to genital herpes and gynaecology. Additional articles were identified through the references of these articles. All study types and recommendation reports were reviewed.

Recommendations: 1. Up to 70% of all genital HSV-2 infections are transmitted during asymptomatic shedding; therefore, the use of condoms is recommended to lessen the likelihood of disease transmission. (II-A) 2. A laboratory-based diagnosis of genital herpes is essential for its effective management. (II-A) 3. Suppressive treatment is suggested for patients who have * at least 6 recurrences per year * significant complications, but fewer than 6 recurrences per year * their quality of life significantly affected * social and sexual dysfunction * to lower the risk of transmission to a sexual partner or fetus/neonate. (II-B) 4. The use of the anti-viral valacyclovir, coupled with condoms and safer sex counselling, is recommended for individuals with proven genital herpes. (I-B) 5. Routine or targeted HSV screening is not indicated.

Publication types

  • Guideline

MeSH terms

  • Acyclovir / analogs & derivatives
  • Acyclovir / therapeutic use
  • Antiviral Agents / therapeutic use*
  • Condoms
  • Female
  • Herpes Genitalis / diagnosis
  • Herpes Genitalis / prevention & control*
  • Herpes Genitalis / therapy*
  • Herpes Genitalis / transmission
  • Humans
  • Mass Screening
  • Sex Counseling*
  • Valacyclovir
  • Valine / analogs & derivatives
  • Valine / therapeutic use

Substances

  • Antiviral Agents
  • Valine
  • Valacyclovir
  • Acyclovir