Immunoglobulin G avidities in infants in Mexico after primary immunization with three doses of polyribosylribitol phosphate-tetanus toxoid Haemophilus influenzae type b vaccine

Clin Vaccine Immunol. 2008 Jun;15(6):1024-7. doi: 10.1128/CVI.00009-08. Epub 2008 Apr 16.

Abstract

Serum immunoglobulin G concentrations and avidities specific to Haemophilus influenzae type b (Hib) were measured in 208 children living in Guadalajara and Mexico City. Protective concentrations were found in 98.9% and 100.0% of participants, respectively. Geometric mean concentrations differed between both populations and/or among age groups. Mean avidities differed only among the 7- to 12-month-old children. Diphtheria-tetanus-whole-cell pertussis-hepatitis B-Hib primary vaccination seems to induce protection in Mexican children.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antibodies, Bacterial / immunology*
  • Antibody Affinity*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Diphtheria-Tetanus-Pertussis Vaccine / immunology*
  • Haemophilus Vaccines / immunology*
  • Haemophilus influenzae type b / immunology*
  • Hepatitis B Vaccines / immunology*
  • Humans
  • Immunoglobulin G / immunology*
  • Infant
  • Mexico
  • Polysaccharides / immunology*
  • Polysaccharides, Bacterial / immunology*

Substances

  • Antibodies, Bacterial
  • Diphtheria-Tetanus-Pertussis Vaccine
  • DtwP-HepB-Hib vaccine
  • Haemophilus Vaccines
  • Hepatitis B Vaccines
  • Immunoglobulin G
  • Polysaccharides
  • Polysaccharides, Bacterial
  • polyribitol phosphate