Antimycobacterial activity of flavonoids from Lantana camara Linn

S Begum; A Wahab; B S Siddiqui

doi:10.1080/14786410600898714

Antimycobacterial activity of flavonoids from Lantana camara Linn

Nat Prod Res. 2008 Apr 15;22(6):467-70. doi: 10.1080/14786410600898714.

Authors

S Begum¹, A Wahab, B S Siddiqui

Affiliation

¹ H.E.J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. sabira@khi.comsats.net.pk

PMID: 18415851
DOI: 10.1080/14786410600898714

Abstract

Linaroside (1) and lantanoside (2), two flavonoids isolated from Lantana camara and their common acetyl derivative (3) were examined for antimycobacterial activity against Mycobacterium tuberculosis, strain H(37)Rv. These compounds exhibited 30, 37 and 98% inhibition, respectively at 6.25 microg mL(-1) concentration. Among these flavonoids acetylated compound was found to be the most active.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antitubercular Agents / isolation & purification*
Antitubercular Agents / pharmacology*
Flavonoids / isolation & purification*
Flavonoids / pharmacology*
Lantana / chemistry*
Mycobacterium tuberculosis / drug effects*
Plant Components, Aerial / chemistry

Substances

Antitubercular Agents
Flavonoids