Conformer independent heterodimerisation of linear arrays using three hydrogen bonds

Chem Commun (Camb). 2008 Jan 21:(3):344-6. doi: 10.1039/b712603d.

Abstract

5-Membered heterocycles are employed to give a conformer independent DDA array of hydrogen bonds, resulting in enhanced binding affinity to a complementary AAD array in comparison to a DDA array employing a 6-membered ring.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Dimerization
  • Heterocyclic Compounds, 4 or More Rings / chemistry*
  • Hydrogen Bonding
  • Models, Molecular
  • Molecular Conformation
  • Stereoisomerism

Substances

  • Heterocyclic Compounds, 4 or More Rings