Abstract
Cancer stem cells (CSCs) are a subpopulation of cancer cells that possess characteristics, including self-renewal, associated with normal stem cells. In this issue of Cell Stem Cell, Wong et al. (2008) define a core embryonic stem cell (ESC)-like gene expression program that may be important for CSC function in multiple epithelial cancers.
MeSH terms
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Adult Stem Cells / cytology
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Adult Stem Cells / physiology*
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Animals
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Biomarkers, Tumor / genetics
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Biomarkers, Tumor / metabolism*
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Cell Transformation, Neoplastic
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Embryonic Stem Cells / cytology
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Embryonic Stem Cells / physiology*
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Epithelium / pathology*
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Humans
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Neoplasms, Experimental / genetics
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Neoplasms, Experimental / metabolism
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Neoplasms, Experimental / pathology*
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Neoplastic Stem Cells / pathology*
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Transcription, Genetic*