The typical hospital and operating theatre present multiple potential hazards to both workers and patients, and protection against some of these is provided through use of various forms of clothing and textiles. While many standards exist for determining the performance of fabrics, most tests are conducted under laboratory conditions and against a single hazard. This paper provides an overview of selected developments in the principal properties of fabrics and garments for use in these workplaces, identifies the key standards, and suggests topics for further investigation.