1H and 13C NMR characteristics of synthetic derivatives of steroid sapogenins. Part III. 16Beta,23:23,26-diepoxy side chains

Ignacio Vázquez-Ramírez; Mariana Macías-Alonso; Rafael O Arcos-Ramos; Karen M Ruíz-Pérez; Diana O Solano-Ramírez; Martín A Iglesias Arteaga

doi:10.1016/j.steroids.2008.01.027

1H and 13C NMR characteristics of synthetic derivatives of steroid sapogenins. Part III. 16Beta,23:23,26-diepoxy side chains

Steroids. 2008 Jul;73(6):642-51. doi: 10.1016/j.steroids.2008.01.027. Epub 2008 Feb 12.

Authors

Ignacio Vázquez-Ramírez¹, Mariana Macías-Alonso, Rafael O Arcos-Ramos, Karen M Ruíz-Pérez, Diana O Solano-Ramírez, Martín A Iglesias Arteaga

Affiliation

¹ Departamento de Química Orgánica, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510 México, D.F., Mexico.

PMID: 18353410
DOI: 10.1016/j.steroids.2008.01.027

Abstract

The full assignments of the (1)H and (13)C NMR signals of steroids bearing the 16beta,23:23,26-diepoxy side chain are provided. Differentiation of the diasterotopic H-26 pair was achieved with the aid of NOESY experiments. The main substituent and steric effects associated with this moiety and their influence on the chemical shifts of the neighboring atoms are discussed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carbon Isotopes
Magnetic Resonance Spectroscopy / methods*
Models, Molecular
Protons
Sapogenins / chemistry*

Substances

Carbon Isotopes
Protons
Sapogenins