Primary multifocal osseous Hodgkin's lymphoma

World J Surg Oncol. 2008 Mar 17:6:34. doi: 10.1186/1477-7819-6-34.

Abstract

Background: Hodgkin's disease (HD) most commonly presents with progressive painless enlargement of peripheral lymph nodes, especially around the cervical region. A few children have systemic symptoms and weight loss. At the time of diagnosis, osseous involvement is uncommon

Case presentation: A case is described of Primary Multifocal Osseous Hodgkin's Lymphoma in a seven-year-old boy. He presented with a painful swelling in the sternum, and further investigations revealed deposits in his L1 vertebra, the left sacro-iliac joint and the right acetabulum.

Conclusion: The clinical, radiological and histological features of this disease can mimic other medical conditions, including Tuberculosis, making the diagnosis difficult and often leading to delays in treatment. This is a very rare condition and we believe this to be the youngest reported case in the literature.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy, Needle
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / drug therapy*
  • Child
  • Follow-Up Studies
  • Hodgkin Disease / diagnosis*
  • Hodgkin Disease / drug therapy*
  • Humans
  • Immunohistochemistry
  • Lumbar Vertebrae / pathology
  • Magnetic Resonance Imaging
  • Male
  • Risk Assessment
  • Severity of Illness Index
  • Sternum / pathology
  • Thoracic Vertebrae / pathology
  • Tomography, X-Ray Computed