Abstract
Photo-onycholysis associated with drugs is an uncommon disorder. We report the case of a woman who developed photo-onycholysis on multiple nails after uptake of olanzapine. Substitution of olanzapine with aripiprazole further exacerbated the problem. The possible mechanisms of photo-onycholysis development by modern atypical antipsychotics, modulating dopamine receptors, are discussed.
MeSH terms
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Antipsychotic Agents / adverse effects
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Antipsychotic Agents / therapeutic use
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Aripiprazole
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Benzodiazepines / adverse effects*
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Benzodiazepines / therapeutic use
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Bipolar Disorder / drug therapy
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Erythema / chemically induced
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Erythema / diagnosis
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Female
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Humans
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Middle Aged
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Olanzapine
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Onycholysis / chemically induced*
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Onycholysis / diagnosis
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Photosensitivity Disorders / chemically induced*
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Photosensitivity Disorders / diagnosis
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Piperazines / adverse effects*
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Piperazines / therapeutic use
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Quinolones / adverse effects*
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Quinolones / therapeutic use
Substances
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Antipsychotic Agents
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Piperazines
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Quinolones
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Benzodiazepines
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Aripiprazole
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Olanzapine