Abstract
Three new sesquiterpenes, 2-deoxy-7-O-methyllemnacarnol (1), 2-deoxy-12 alpha-ethoxy-7-O-methyllemnacarnol (2), and 2-deoxy-12 alpha-methoxy-7-O-methyllemnacarnol (3), were isolated from a soft coral Nephthea sp. collected in Indonesia, together with five known sesquiterpenes. The structures of the new compounds were assigned on the basis of their spectroscopic data.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anthozoa / chemistry*
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / isolation & purification
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Antineoplastic Agents / pharmacology
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Cell Proliferation / drug effects
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Cricetinae
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Cricetulus
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Indonesia
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Leukemia P388 / drug therapy
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Magnetic Resonance Spectroscopy
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Mice
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Sesquiterpenes / chemistry*
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Sesquiterpenes / isolation & purification
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Sesquiterpenes / pharmacology
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Spectrometry, Mass, Electrospray Ionization
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
Substances
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2-deoxy-12 alpha-ethoxy-7-O-methyllemnacarnol
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2-deoxy-12 alpha-methoxy-7-O-methyllemnacarnol
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2-deoxy-7-O-methyllemnacarnol
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Antineoplastic Agents
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Sesquiterpenes