Hydrolase-catalyzed biotransformations in deep eutectic solvents

Johnathan T Gorke; Friedrich Srienc; Romas J Kazlauskas

doi:10.1039/b716317g

Hydrolase-catalyzed biotransformations in deep eutectic solvents

Chem Commun (Camb). 2008 Mar 14:(10):1235-7. doi: 10.1039/b716317g. Epub 2008 Jan 31.

Authors

Johnathan T Gorke¹, Friedrich Srienc, Romas J Kazlauskas

Affiliation

¹ Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, MN 55455, USA.

PMID: 18309428
DOI: 10.1039/b716317g

Abstract

Hydrolases show good catalytic activity in deep eutectic solvents, despite the presence of urea, which can denature enzymes, or alcohols, which can interfere with hydrolase-catalyzed reactions.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Biotransformation
Catalysis
Hydrolases / metabolism*
Solvents / chemistry*

Substances

Solvents
Hydrolases