Predicting fluorouracil toxicity: can we finally do it?

MeSH terms

• Antimetabolites, Antineoplastic / adverse effects*
• Diarrhea / chemically induced
• Diarrhea / etiology*
• Diarrhea / genetics
• Dihydrouracil Dehydrogenase (NADP) / genetics
• Fluorouracil / adverse effects*
• Genetic Predisposition to Disease
• Genetic Testing*
• Humans
• Leucovorin / adverse effects
• Leukopenia / chemically induced
• Leukopenia / etiology*
• Leukopenia / genetics
• Logistic Models
• Methylenetetrahydrofolate Reductase (NADPH2) / genetics
• Mucositis / chemically induced
• Mucositis / etiology*
• Mucositis / genetics
• Odds Ratio
• Patient Selection
• Polymorphism, Genetic*
• Predictive Value of Tests
• Risk Assessment
• Risk Factors
• Severity of Illness Index
• Thymidylate Synthase / genetics
• Vitamin B Complex / adverse effects