Face cancer is one of the most common skin tumors and because of its locations is usually early diagnosed. In spite of this a lot of recurrence after surgical treatment are observed. It is caused a lack of proper margins in sequence of limitation excision because of esthetic and functional reasons. The recurrence of skin cancer primarily localized in periocular region and infiltrating intraorbital, ethmoidal and nasal tissues demand extensive and injurious surgical procedures. The authors present their experience in diagnostic and treatment patients with recurrent cancers infiltrating of ethmoid-orbito-nasal complex.