Dramatic improvement following interleukin 1beta blockade in tumor necrosis factor receptor-1-associated syndrome (TRAPS) resistant to anti-TNF-alpha therapy

J Rheumatol. 2008 Feb;35(2):357-8.

Authors

Karim Sacré, Benoit Brihaye, Olivier Lidove, Thomas Papo, Marie-Annick Pocidalo, Laurence Cuisset, Catherine Dodé

PMID: 18260167

No abstract available

Publication types

Letter

MeSH terms

Adult
Autoimmune Diseases* / drug therapy
Autoimmune Diseases* / genetics
C-Reactive Protein / drug effects
Familial Mediterranean Fever* / drug therapy
Familial Mediterranean Fever* / genetics
Female
Humans
Immunologic Factors / therapeutic use
Interleukin 1 Receptor Antagonist Protein / therapeutic use*
Interleukin-1beta / antagonists & inhibitors*
Mutation, Missense / genetics
Receptors, Tumor Necrosis Factor, Type I / genetics*
Syndrome
Tumor Necrosis Factor-alpha / antagonists & inhibitors

Substances

Immunologic Factors
Interleukin 1 Receptor Antagonist Protein
Interleukin-1beta
Receptors, Tumor Necrosis Factor, Type I
Tumor Necrosis Factor-alpha
C-Reactive Protein