Abstract
Two new prenylated dihydroflavanoids have been isolated from the medicinal plant of Dolichos tenuicaulis (Baker) Craib. Their structures were elucidated as (2S)-5,2',6'-trihydroxy-8-prenyl-6,7-(3-prenyl-2,2-dimethylpyrano)-3',4'-(2,2-dimethyl-1-keone-cyclohexadiene)-flavanone (1) and (2S)-5,2',6'-trihydroxy-8-prenyl-6,7-(3-prenyl-2,2-dimethyl-1-keone-cyclohexadiene)-flavanone (2) on the basis of spectroscopic analysis.
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / pharmacology
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Cell Line, Tumor
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Cyclohexenes / chemistry*
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Cyclohexenes / pharmacology*
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Dolichos / chemistry*
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Flavanones / chemistry*
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Flavanones / pharmacology*
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Flavonoids / chemistry*
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Flavonoids / pharmacology*
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Humans
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Molecular Structure
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Neoplasms / drug therapy
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Plant Roots / chemistry
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Plants, Medicinal / chemistry*
Substances
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(2S)-5,2',6'-trihydroxy-8-prenyl-6,7-(3-prenyl-2,2-dimethyl-1-keone-cyclohexadiene)-flavanone
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(2S)-5,2',6'-trihydroxy-8-prenyl-6,7-(3-prenyl-2,2-dimethylpyrano)-3',4'-(2,2-dimethyl-1-keone-cyclohexadiene)-flavanone
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Antineoplastic Agents, Phytogenic
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Cyclohexenes
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Flavanones
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Flavonoids