EPA's 2006 human-subjects rule for pesticide experiments

Account Res. 2007 Oct-Dec;14(4):211-54. doi: 10.1080/08989620701670161.

Abstract

Arguing that the 2006 Environmental Protection Agency (EPA) human-subjects rule allows use of unethical third-party research (on pregnant women and children) in setting pesticide regulations, this article first (a) provides a brief history of U.S. pesticide regulation, particularly regarding childhood safety. Next it (b) outlines ethical and scientific loopholes in the 2006 EPA rule; (c) shows how the Human Subjects Review Board, mandated by the 2006 rule, has been implemented in flawed ways; and (d) illustrates that one source of problems with the rule may be influence by those with conflicts of interest.

Publication types

  • Review

MeSH terms

  • Chemical Industry / legislation & jurisprudence
  • Chemical Industry / standards
  • Child Welfare* / ethics
  • Child Welfare* / legislation & jurisprudence
  • Child, Preschool
  • Conflict of Interest
  • Ethics Committees, Research / legislation & jurisprudence
  • Ethics Committees, Research / standards
  • Female
  • Government Regulation*
  • Guideline Adherence / ethics*
  • Guideline Adherence / legislation & jurisprudence
  • Guideline Adherence / standards
  • Human Experimentation / ethics
  • Human Experimentation / legislation & jurisprudence
  • Human Experimentation / standards*
  • Humans
  • Pesticides / toxicity*
  • Politics
  • Pregnancy
  • Pregnant Women*
  • Toxicity Tests / ethics
  • Toxicity Tests / standards
  • United States
  • United States Environmental Protection Agency / ethics
  • United States Environmental Protection Agency / standards*

Substances

  • Pesticides