The alteration of autonomic function in multiple organ dysfunction syndrome

Hendrik Schmidt; Dirk Hoyer; Joachim Wilhelm; Gerold Söffker; Konstantin Heinroth; Kuno Hottenrott; Samir M Said; Michael Buerke; Ursula Müller-Werdan; Karl Werdan

doi:10.1016/j.ccc.2007.10.003

The alteration of autonomic function in multiple organ dysfunction syndrome

Crit Care Clin. 2008 Jan;24(1):149-63, ix. doi: 10.1016/j.ccc.2007.10.003.

Authors

Hendrik Schmidt¹, Dirk Hoyer, Joachim Wilhelm, Gerold Söffker, Konstantin Heinroth, Kuno Hottenrott, Samir M Said, Michael Buerke, Ursula Müller-Werdan, Karl Werdan

Affiliation

¹ Martin-Luther-University Halle-Wittenberg, Klinikum Kröllwitz, Ernst-Grube-Strasse 40, D-06097 Halle/Saale, Germany. hendrik.schmidt@medizin.uni-halle.de

PMID: 18241783
DOI: 10.1016/j.ccc.2007.10.003

Abstract

Autonomic dysfunction is associated with the severity of illness and mortality in patients with multiple organ dysfunction syndrome (MODS) and may contribute significantly to the pathogenesis of this syndrome. Several treatment approaches may possibly restore autonomic function in MODS and thus cause the survival benefit.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Autonomic Nervous System Diseases / complications
Autonomic Nervous System Diseases / drug therapy
Autonomic Nervous System Diseases / physiopathology*
Baroreflex / physiology*
Chemoreceptor Cells / physiology
Critical Care / trends*
Heart Rate
Humans
Multiple Organ Failure / classification
Multiple Organ Failure / etiology
Multiple Organ Failure / physiopathology*
Severity of Illness Index