Fatal neonatal stroke from a prenatal cardiac thrombus

Pediatr Neurol. 2008 Feb;38(2):140-2. doi: 10.1016/j.pediatrneurol.2007.10.003.

Abstract

Despite careful investigation, the etiology of many perinatal arterial strokes is unknown. We report on a 5-day-old boy with a cardiac thrombus of prenatal origin resulting in a fatal postnatal stroke. The thrombus was discovered only at autopsy, challenging the assumption of a placental source of embolus in perinatal strokes in the absence of macroscopic and microscopic examination of the heart.

Publication types

  • Case Reports

MeSH terms

  • Acidosis / etiology
  • Autopsy
  • Brain Edema / congenital
  • Brain Edema / pathology
  • Coronary Thrombosis / complications*
  • Coronary Thrombosis / pathology
  • Fatal Outcome
  • Fetal Diseases*
  • Humans
  • Infant, Newborn
  • Male
  • Myocardium / pathology
  • Respiratory Distress Syndrome, Newborn / etiology
  • Stroke / congenital*
  • Stroke / etiology*
  • Stroke / pathology
  • Tachycardia / etiology
  • Tomography, X-Ray Computed