Frequency-coded chemical sensors

Anal Chem. 2008 Feb 1;80(3):606-11. doi: 10.1021/ac7016162. Epub 2007 Dec 29.

Abstract

We have developed a new method to intelligently sample analytes and introduce the analytes to sensors. The method automatically adjusts sampling duration according to the sensors' response to the analytes and converts the amplitude of the sensor output to a frequency output, giving us another opportunity to reduce noise in the signal. It also addresses some of the common sensor issues such as response time, saturation, chemical dynamic range, and sensor protection, saving precious detection time, protecting sensors, and enabling sensitive sensors built for low-concentration detection to be used for high-concentration detection as well. We have put together a system using a tuning fork chemical sensor as a sample sensor to demonstrate the feasibility and benefits of the new sensing technique.