SREBP1 interaction with prelamin A forms: a pathogenic mechanism for lipodystrophic laminopathies

Adv Enzyme Regul. 2008:48:209-23. doi: 10.1016/j.advenzreg.2007.11.003. Epub 2007 Nov 19.

Authors

Nadir M Maraldi¹, Cristina Capanni, Giovanna Lattanzi, Daria Camozzi, Andrea Facchini, Francesco A Manzoli

Affiliation

¹ Laboratory of Cell Biology, IOR, Bologna, Italy. maraldi@area.bo.cnr.it

PMID: 18155670
DOI: 10.1016/j.advenzreg.2007.11.003

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

3T3-L1 Cells / cytology
3T3-L1 Cells / physiology
Adipocytes / cytology
Animals
Cell Differentiation / physiology
Humans
Lamin Type A / genetics
Lamin Type A / physiology
Lipodystrophy / etiology*
Lipodystrophy / genetics
Metabolic Syndrome / etiology
Mice
Models, Biological
Nuclear Proteins / metabolism*
PPAR gamma / biosynthesis
Prenylation
Protein Precursors / metabolism*
Protein Structure, Quaternary
Protein Transport
Sterol Regulatory Element Binding Protein 1 / metabolism*

Substances

Lamin Type A
Nuclear Proteins
PPAR gamma
Protein Precursors
SREBF1 protein, human
Sterol Regulatory Element Binding Protein 1
lamin C
prelamin A