Abstract
We report the case of an adult male patient with Tourette syndrome, self-injurious behavior and depression, refractory to conventional treatment, and whose symptoms remitted after electroconvulsive therapy. Serial Technetium 99m-Ethyl-Cysteinate-Dimer single photon emission tomographies were applied, before, during, and after electroconvulsive therapy. The neural substrates of this treatment process were further analyzed by woxel-wise subtracted single photon emission tomography images.
MeSH terms
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Adult
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Brain / blood supply
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Brain / diagnostic imaging*
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Brain / physiopathology
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Brain Mapping
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Brief Psychiatric Rating Scale
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Cerebral Cortex / blood supply
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Cerebral Cortex / diagnostic imaging
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Cerebral Cortex / physiopathology
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Combined Modality Therapy
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Cysteine / analogs & derivatives
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Depressive Disorder / diagnostic imaging
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Depressive Disorder / physiopathology
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Depressive Disorder / therapy
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Electroconvulsive Therapy*
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Humans
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Image Processing, Computer-Assisted*
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Magnetic Resonance Imaging*
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Male
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Neurologic Examination
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Organotechnetium Compounds
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Psychotropic Drugs / administration & dosage
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Regional Blood Flow / physiology
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Self-Injurious Behavior / diagnostic imaging
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Self-Injurious Behavior / physiopathology
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Self-Injurious Behavior / therapy
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Subtraction Technique
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Tomography, Emission-Computed, Single-Photon*
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Tourette Syndrome / diagnostic imaging*
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Tourette Syndrome / physiopathology
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Tourette Syndrome / therapy*
Substances
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Organotechnetium Compounds
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Psychotropic Drugs
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technetium Tc 99m bicisate
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Cysteine