A fast, simple calibration method for organic carbon isotope analysis using continuous-flow elemental analyzer interfaced with an isotope ratio mass spectrometer

Anal Sci. 2007 Dec;23(12):1447-9. doi: 10.2116/analsci.23.1447.

Abstract

Continuous flow analysis using an elemental analyzer interfaced with an isotope ratio mass spectrometer (EA-IRMS) is faster and requires much less material than conventional analytical methods. Although using an EA-IRMS is simple and fast, accurate calibration strongly depends on matching sample and reference peak heights by adjusting the sample weight. This paper describes a new modification for calibration using only the major ion beam intensity (nA) without weighing each sample or increasing the number of reference materials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Calibration
  • Carbon Isotopes / analysis*
  • Geologic Sediments / analysis
  • Indicators and Reagents
  • Mass Spectrometry / methods*
  • Mass Spectrometry / standards
  • Organic Chemicals / analysis*
  • Reference Standards

Substances

  • Carbon Isotopes
  • Indicators and Reagents
  • Organic Chemicals