Abstract
A diastereomerically enriched analogue of 1,3,5-triaza-7-phosphaadamantane (PTA) was obtained by the reaction of PTA lithium salt with benzaldehyde to give the water-soluble derivative phenyl(1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]dec-6-yl)methanol (PZA, 1) as a mixture of two diastereoisomers. PZA derivatives phenyl(1,3,5-triaza-7-phospha-tricyclo[3.3.1.13,7]dec-6-yl)methanol sulfide [PZA(S), 2] and oxide [PZA(O), 3] were also synthesized. The latter was isolated in the solid state, and the X-ray crystal structure of a single diastereoisomer was obtained. Compound 1 was used as a k1-P monodentate ligand toward iridium(III) moieties, and the piano-stool complex [Cp*IrCl2(PZA)] (4) was obtained as a mixture of diastereoisomers both in solution and in the solid state.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adamantane / analogs & derivatives*
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Adamantane / chemistry
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Crystallography, X-Ray
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Heterocyclic Compounds, 3-Ring / chemical synthesis*
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Heterocyclic Compounds, 3-Ring / chemistry
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Iridium / chemistry*
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Lithium / chemistry
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Models, Molecular
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Molecular Conformation
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Organometallic Compounds / chemistry*
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Organophosphorus Compounds / chemical synthesis*
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Organophosphorus Compounds / chemistry*
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Oxides / chemistry*
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Phosphines / chemistry*
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Salts / chemistry
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Solubility
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Stereoisomerism
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Sulfides / chemical synthesis*
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Sulfides / chemistry
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Water / chemistry
Substances
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1,3,5-triaza-7-phosphaadamantane
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Heterocyclic Compounds, 3-Ring
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Organometallic Compounds
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Organophosphorus Compounds
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Oxides
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Phosphines
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Salts
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Sulfides
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phenyl(1,3,5-triaza-7-phosphatricyclo(3.3.1.1(3,7))dec-6-yl)methanol
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Water
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Iridium
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Lithium
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Adamantane