Macrophage receptors implicated in the "adaptive" form of innate immunity

Microbes Infect. 2007 Nov-Dec;9(14-15):1680-7. doi: 10.1016/j.micinf.2007.09.002. Epub 2007 Sep 14.

Abstract

The adaptive component of innate immunity occurs during the course of infection when antigen presenting cells alter expression of soluble or surface associated pattern recognition receptors. This results in increased recognition of a broad spectrum of pathogens, enhancement of effector functions and altered regulation of the inflammatory response.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • C-Reactive Protein / metabolism
  • Host-Pathogen Interactions
  • Humans
  • Immunity, Active*
  • Immunity, Innate*
  • Lectins, C-Type
  • Macrophages / immunology
  • Macrophages / metabolism*
  • Membrane Proteins / metabolism
  • Mice
  • Nerve Tissue Proteins / metabolism
  • Receptors, Immunologic / metabolism*
  • Receptors, Scavenger / metabolism
  • Serum Amyloid P-Component / metabolism

Substances

  • Lectins, C-Type
  • Membrane Proteins
  • Nerve Tissue Proteins
  • Receptors, Immunologic
  • Receptors, Scavenger
  • Serum Amyloid P-Component
  • dectin 1
  • PTX3 protein
  • C-Reactive Protein