Synthesis of (R)-2-(benzyloxy)-tetrahydro-5,5-dimethylfuran by a new oxidative rearrangement

David Díez; Marta G Nuñez; Rosalina F Moro; Narciso M Garrido; Isidro S Marcos; Pilar Basabe; Julio G Urones

doi:10.3390/11120959

Synthesis of (R)-2-(benzyloxy)-tetrahydro-5,5-dimethylfuran by a new oxidative rearrangement

Molecules. 2006 Dec 18;11(12):959-67. doi: 10.3390/11120959.

Authors

David Díez¹, Marta G Nuñez, Rosalina F Moro, Narciso M Garrido, Isidro S Marcos, Pilar Basabe, Julio G Urones

Affiliation

¹ Departamento de Química Orgánica,Universidad de Salamanca, Plaza de los Caídos 1-5, 37008 Salamanca, Spain. ddm@usal.es

Abstract

The rearrangement under oxidative conditions of 3-(benzyloxy)-tetrahydro- 2,6,6-trimethyl-2H-pyran-2-carbaldehydes to afford a chiral protected tetrahydrofuran lactol is described.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry
Furans / chemical synthesis*
Furans / chemistry
Oxidation-Reduction

Substances

2-(benzyloxy)-tetrahydro-5,5-dimethylfuran
Aldehydes
Furans