Abstract
An easy and safe, though only moderately effective method is presented for preparing (diacetoxyiodo)arenes, ArI(OAc)2, from iodoarenes, ArI, using the commercially available and easily handled urea-hydrogen peroxide adduct (UHP) as the oxidant. The reactions take place in anhydrous AcOH/Ac2O/AcONa (a catalyst)mixtures, at 40 oC for 3.5 h to afford the purified ArI(OAc)2 in 37-78% yields. The fully interpreted (1)H- and (13)C-NMR spectra of the ArI(OAc)2 products are reported.
MeSH terms
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Carbamide Peroxide
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Carbon Isotopes / chemistry*
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Chemistry, Organic / methods*
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Drug Combinations
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Hydrogen / chemistry*
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Iodine Compounds / chemical synthesis*
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Magnetic Resonance Spectroscopy
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Naphthalenes / chemical synthesis*
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Oxidants / pharmacology
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Peroxides / pharmacology*
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Transition Temperature
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Urea / analogs & derivatives*
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Urea / pharmacology
Substances
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Carbon Isotopes
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Drug Combinations
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Iodine Compounds
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Naphthalenes
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Oxidants
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Peroxides
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Carbamide Peroxide
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Hydrogen
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Urea