The first direct C-H arylation of purine nucleosides

Chem Commun (Camb). 2007 Dec 7:(45):4729-30. doi: 10.1039/b714253f. Epub 2007 Oct 25.

Abstract

Pd-catalyzed direct C-H arylation of unprotected purine nucleosides with aryl iodides at position 8 was developed to allow a straightforward single-step introduction of diverse aryl groups.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon / chemistry*
  • Hydrogen / chemistry*
  • Molecular Structure
  • Nucleosides / chemistry*
  • Purines / chemistry*

Substances

  • Nucleosides
  • Purines
  • Carbon
  • Hydrogen
  • purine