Localized high-resolution MR imaging of rat brain architecture using micro-fabricated receive-only RF coil

Meng-Chi Hsieh; Li-Wei Kuo; Edzer L Wu; Jyh-Horng Chen

doi:10.1109/IEMBS.2007.4353734

Localized high-resolution MR imaging of rat brain architecture using micro-fabricated receive-only RF coil

Annu Int Conf IEEE Eng Med Biol Soc. 2007:2007:6074-7. doi: 10.1109/IEMBS.2007.4353734.

Authors

Meng-Chi Hsieh¹, Li-Wei Kuo, Edzer L Wu, Jyh-Horng Chen

Affiliation

¹ Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan. stanleyhsieh@me.ee.ntu.edu.tw

PMID: 18003400
DOI: 10.1109/IEMBS.2007.4353734

Abstract

This study introduced a localized approach for magnetic resonance microscopy (MRM) of the rat brain. A single-loop radiofrequency (RF) receiver coil designed for micro-imaging was developed by using electromagnetic simulation software widely used in communication fields. With transmit-only and receive-only (TORO) configuration, receive-only surface coil can achieve higher signal-to-noise ratio (SNR) at localized brain region. Corpus callosum and hippocampus were landmarks to evaluate the capacity of the proposed coil. On a 3T MRI system, high-resolution MRI of the dissected rat brain was acquired with spatial resolution of 117x117x500 microm3. The achieved high local SNR and spatial resolution will provide valuable information for resolving the architecture of the rat brain.

Publication types

Evaluation Study

MeSH terms

Animals
Equipment Design
Equipment Failure Analysis
Hippocampus / cytology*
Magnetic Resonance Imaging / instrumentation*
Magnetic Resonance Imaging / veterinary*
Magnetics / instrumentation*
Miniaturization
Rats
Transducers*