Fast, efficient Ru(IV)-catalysed regioselective allylation of indoles using allyl alcohol (without additives) under mild conditions

Chem Commun (Camb). 2007 Nov 28:(44):4692-3. doi: 10.1039/b710763c. Epub 2007 Oct 15.

Abstract

The new Ru(IV) salt, [Ru(eta(3)-C(3)H(5))(Cp*)(CH(3)CN)(2)](PF(6))(2), is an excellent catalyst for the regioselective allylation of a variety of indole compounds using allyl alcohol as substrate; there are no co-catalysts required in this chemistry and the yields and reaction conditions are very favorable.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkylation
  • Catalysis
  • Indoles / chemical synthesis*
  • Indoles / chemistry
  • Molecular Structure
  • Organometallic Compounds / chemistry*
  • Propanols / chemistry*
  • Ruthenium / chemistry*
  • Stereoisomerism

Substances

  • Indoles
  • Organometallic Compounds
  • Propanols
  • allyl alcohol
  • Ruthenium