Molecular diversity of Brazilian strains of porcine circovirus type 2 (PCV-2)

Res Vet Sci. 2008 Aug;85(1):197-200. doi: 10.1016/j.rvsc.2007.07.009. Epub 2007 Oct 31.

Abstract

Porcine circovirus 2 (PCV-2) is associated with a broad range of syndromes. In this study, eight pig tissue samples from two Brazilian states were analyzed using six PCR primer pairs amplifying a 1705-bp fragment of the PCV-2 genome. The NJ distance-based method was used for the phylogenetic analysis with the eight field strains herein, 15 GenBank sequences and using PCV-1 as an out-group. This yielded two major clusters (A and B) for this viral species, with the Brazilian strains segregating with European and Asian sequences. Nucleotide identity was 99.7 to 100% among the sequences. This information can be used in further studies of pathogenesis related to PCV-2 in Brazil.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brazil / epidemiology
  • Circoviridae Infections / epidemiology
  • Circoviridae Infections / veterinary*
  • Circoviridae Infections / virology
  • Circovirus / classification*
  • Circovirus / genetics*
  • Genetic Variation
  • Swine