One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling

Chem Commun (Camb). 2007 Nov 21:(43):4516-8. doi: 10.1039/b707899d. Epub 2007 Sep 5.

Abstract

One-pot N-arylation and oxidative coupling can be promoted by a common palladium catalyst in the presence of appropriate additives: palladium-catalyzed N-arylation of anilines with aryl triflates under the standard conditions followed by addition of acetic acid under oxygen or air atmosphere afforded various types of functionalized carbazoles in good to excellent yields.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aniline Compounds / chemistry*
  • Carbazoles / chemical synthesis*
  • Catalysis
  • Mesylates / chemistry
  • Oxidation-Reduction
  • Palladium / chemistry

Substances

  • Aniline Compounds
  • Carbazoles
  • Mesylates
  • Palladium
  • trifluoromethanesulfonic acid