NMR methods for studying quadruplex nucleic acids

Methods. 2007 Dec;43(4):264-77. doi: 10.1016/j.ymeth.2007.05.007.

Abstract

Solution NMR spectroscopy has traditionally played a central role in examining quadruplex structure, dynamics, and interactions. Here, an overview is given of the methods currently applied to structural, dynamics, thermodynamics, and kinetics studies of nucleic acid quadruplexes and associated cations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • G-Quadruplexes*
  • Guanine / chemistry*
  • Kinetics
  • Ligands
  • Magnetic Resonance Spectroscopy / methods*
  • Thermodynamics

Substances

  • Ligands
  • Guanine