[Fever, pneumonia and eosinophilia]

Praxis (Bern 1994). 2007 Oct 3;96(40):1543-7. doi: 10.1024/1661-8157.96.40.1543.
[Article in German]

Abstract

We present the case of a 71-year old man with acute eosinophilic pneumonia. By ruling out other common etiologies and by a positive lymphocyte transformation test the non-steroidal anti-inflammatory drug mefenamic acid was identified as the possible causative agent or this potentially life threatening lung disease. The clinical presentation, diagnosis, and treatment of acute eosinophilic pneumonia as a pulmonary manifestation of a drug-induced allergic reaction are discussed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Bronchoalveolar Lavage Fluid / immunology
  • Diagnosis, Differential
  • Drug Hypersensitivity / diagnosis*
  • Drug Hypersensitivity / pathology
  • Eosinophilia / etiology*
  • Eosinophils / pathology
  • Fever of Unknown Origin / etiology*
  • Humans
  • Male
  • Mefenamic Acid / adverse effects*
  • Mefenamic Acid / therapeutic use
  • Osteoarthritis, Hip / drug therapy*
  • Pulmonary Eosinophilia / chemically induced*
  • Pulmonary Eosinophilia / diagnosis
  • Pulmonary Eosinophilia / pathology

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Mefenamic Acid