The measurement of compound neural action potential in sciatic nerve using microelectrode array

Conf Proc IEEE Eng Med Biol Soc. 2006:Suppl:6743-6. doi: 10.1109/IEMBS.2006.260936.

Abstract

As a method of observing regeneration of damaged nerves, research is being conducted on analyzing the electric signals of nerve fibers that are damaged and regenerating by implanting a microelectrode array between those nerves. Microelectrode arrays possess high impedance and a unique phase characteristic according to their structural features,thus it requires a phase linearity test and an impedance test to prevent neural signal distortion.Therefore, this paper analyzes the features of microelectrode array and designs a bioamplifier. We also measured signals from sciatic nerves in rats with microelectrode array.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology*
  • Animals
  • Electric Impedance
  • Electric Stimulation
  • Mice
  • Microelectrodes
  • Nerve Regeneration / physiology*
  • Rats
  • Sciatic Nerve / physiology*