Survey of the anticoccidial feed additive nicarbazin (as dinitrocarbanilide residues) in poultry and eggs

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Jan;25(1):32-40. doi: 10.1080/02652030701552956. Epub 2007 Oct 22.

Abstract

A survey was carried out on the occurrence of dinitrocarbanilide (DNC), the marker residue for nicarbazin, in poultry produced in Ireland during 2002-2004. Liver (n = 736) and breast muscle samples (n = 342) were tested. DNC residues were found in 40 and 26% of liver and breast muscle samples at levels greater than 12.5 and 5 microg kg(-1), respectively. DNC residues were found at >200 microg kg(-1) in 12 and 0% of liver and muscle samples, respectively. Samples of breast muscle (n = 217) imported from 11 countries were also tested for DNC residues. A lower incidence of DNC residues (6%) was found in imported breast muscle. Egg samples (n = 546) were tested and DNC residues were found in nine samples, with levels ranging between 14 and 122 microg kg(-1). Analysis of poultry, carried out as part of official food inspection in the period 2004-2006, indicated a reduction in the number of broiler liver samples containing DNC at >200 microg kg(-1), to approximately 7%. Low levels of DNC residues continue to be found in <2% of egg samples.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Feed / analysis
  • Animals
  • Chromatography, High Pressure Liquid / methods
  • Coccidiostats / analysis*
  • Drug Residues / analysis
  • Eggs / analysis*
  • Food Additives / analysis
  • Ireland
  • Liver / chemistry
  • Mass Spectrometry / methods
  • Meat / analysis*
  • Nicarbazin / analysis*
  • Poultry / metabolism*

Substances

  • Coccidiostats
  • Food Additives
  • Nicarbazin