Accuracy of QT measurement in the EASI-derived 12-lead ECG

Conf Proc IEEE Eng Med Biol Soc. 2006:2006:3986-9. doi: 10.1109/IEMBS.2006.259718.

Abstract

The purpose of this study is to assess QT interval measurements from the EASI 12-lead ECG as compared to the standard 12-lead ECG. The QT interval was automatically measured in simultaneously recorded standard and EASI 12-lead ECGs, using a validated wavelet-based delineator. The agreement between the two sets of measurements was quantified both on a lead-by-lead basis and a multilead basis. The results show an acceptable agreement between QT measurements in the two lead systems, with correlation coefficients (CC) 0.91-0.98 depending on the lead. Standard deviations range from 9.2 ms to 26.4 ms depending on the selected lead. In a few patients large inter-system differences were found, mainly due to different T wave morphologies. Using a multilead delineation, QT intervals were considerably more stable than single-lead measurements and resulted in a much better agreement between the two lead systems (CC: 0.98, QT difference: 1.1 ms +/- 9.8 ms). Thus, EASI-derived 12-lead ECG may be used for reliable QT monitoring when the multilead delineation approach is adopted.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diagnosis, Computer-Assisted
  • Electrocardiography / methods*
  • Electrodes
  • Electrophysiology / methods
  • Equipment Design
  • Humans
  • Long QT Syndrome / diagnosis*
  • Long QT Syndrome / physiopathology*
  • Observer Variation
  • Reproducibility of Results
  • Sensitivity and Specificity