Formation of salts with hydrobromic acid determines the antiarrhythmic effect of lappaconitine derivatives

Dokl Biol Sci. 2007 Jul-Aug:415:265-6. doi: 10.1134/s0012496607040047.

Authors

T G Tolstikova¹, A O Bryzgalov, I V Sorokina, M P Dolgikh, E E Shul'ts, S A Osadchii, G A Tolstikov

Affiliation

¹ Novosibirsk Institute of Organic Chemistry, Siberian Division, Russian Academy of Sciences, pr. Akademika Lavrent'eva 9, Novosibirsk, 630090 Russia.

PMID: 17929661
DOI: 10.1134/s0012496607040047

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aconitine / analogs & derivatives*
Aconitine / chemistry
Aconitine / pharmacology
Animals
Anti-Arrhythmia Agents / pharmacology*
Drug Synergism
Hydrobromic Acid / chemistry*
Rats
Structure-Activity Relationship

Substances

Anti-Arrhythmia Agents
Hydrobromic Acid
Aconitine
lappaconitine