Purpose: To investigate the status of administration of antibiotics drugs for pediatric in-patients in the Department of Oral and Maxillofacial Surgery in our hospital and offer guides for rational use of antibiotics in clinical practice.
Methods: 102 medical records of children from 3 months to 18 years in the Department of Oral and Maxillofacial Surgery in our hospital from the year of 2005-2006 were selected randomly. They were required to fill in the questionnaire which included gender, age, diagnosis of diseases, situation of medicine, laboratory examination, bacterial culture and sensitivity test of medicine. Respective analysis was done over the aspects of the variation of antibiotics medication, duration of medication, drug combination, various choices of antibiotics during the treatment and the ways of administration. A conclusion was drawn of whether the administration of antibiotics was rational.
Results: The rate of antibiotics administration was 94.12%, and the rates of single drug and combined administration (two drugs) were 74.51% and 19.61% respectively. Intravenous drip was the main way of administration, 54 cases received antibiotics orally, none of them received intramuscular medication. The rate of changing two kinds of antibiotics,three kinds of antibiotics and four kinds of antibiotics were 36.27%,23.53% and 9.8% respectively. The rate of bacterial culture was 1.96%. The rate of duration of medication in less than three days, from three days to seven days and more than seven days were 24.50%,48.04% and 21.57% respectively. The administration frequence was higher in cephalosporins, lincosamides, penecillins category than in other antibiotics.
Conclusion: Rational use of anti-bacteria drugs was the main trend, however some problems still existed such as prophylactic administration of antibiotics, low delivery ratio of sample collection, irrational use of drugs, frequent change of antibiotics and drug abuse etc. Therefore, more efficient measures should be developed and implemented such as rational layout of wards, enhancing preoperative health care and rational administration of antibiotics etc.