How to improve skin notation. Position paper from a workshop

Regul Toxicol Pharmacol. 2007 Dec;49(3):301-7. doi: 10.1016/j.yrtph.2007.08.008. Epub 2007 Aug 30.

Abstract

The ICOH Scientific Committee on Occupational and Environmental Dermatoses organized an International Workshop on "Dermal risk assessment at workplace" with the aim of focussing on the different ways of approaching the concept of skin notation (S) for chemicals. The Workshop participants presented their ideas on several aspects of S such as the problems related to the absorption through the compromised skin, the different approaches to S and models that can be used as alternatives to S. Participants agreed to produce a position paper with the goal of exploring the actions needed to improve the S system towards international harmonization. They consider that further discussions are needed to obtain an international consensus, but at the same time they believe that by improving and harmonizing systems for setting S we can make an important contribution to improving health of people with potential dermal exposure to chemicals at work.

Publication types

  • Congress

MeSH terms

  • Animals
  • Humans
  • Occupational Exposure / adverse effects
  • Occupational Exposure / analysis
  • Risk Assessment / methods
  • Skin / drug effects*
  • Skin / metabolism
  • Skin Absorption / drug effects*
  • Toxicology / methods
  • Toxicology / trends