Apotirucallane and tirucallane triterpenoids from Cedrela sinensis

Chem Pharm Bull (Tokyo). 2007 Oct;55(10):1442-7. doi: 10.1248/cpb.55.1442.

Abstract

Nine new triterpenoids, 1-9, were isolated from the cortex of Cedrela sinensis (Meliaceae), together with six known compounds, sapelin E acetate, grandifoliolenone, azadirone, bourjotinolone A, piscidinol A, and hispidol B. The structures of 1-9 were determined by the 2D NMR experiments, chemical methods, and X-ray crystallography.

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Cedrela / chemistry*
  • Crystallography, X-Ray
  • Limonins / chemistry
  • Limonins / isolation & purification
  • Limonins / pharmacology
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plants, Medicinal / chemistry*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification
  • Triterpenes / pharmacology*

Substances

  • Antineoplastic Agents, Phytogenic
  • Limonins
  • Triterpenes
  • apotirucallane
  • azadirone