Hypoglycemic and antihyperglycemic effect of leaves of Vinca rosea linn

Indian J Physiol Pharmacol. 1991 Jul;35(3):145-51.

Abstract

Oral administration of water fraction of alcoholic extract of leaves of Vinca rosea (fam. apocynaeceae) led to marked lowering of blood glucose level in normal and streptozotocin induced diabetic rats. The hypoglycemic effect of the fraction was comparable with that of tolbutamide.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Oral
  • Animals
  • Blood Glucose / drug effects*
  • Blood Glucose / metabolism
  • Diabetes Mellitus, Experimental / drug therapy
  • Drug Interactions
  • Female
  • Glucose / administration & dosage
  • Glucose / metabolism
  • Glucose Tolerance Test
  • Hypoglycemic Agents / pharmacology*
  • Insulin / pharmacology
  • Male
  • Plant Extracts / pharmacology*
  • Plants, Medicinal*
  • Rats
  • Rats, Inbred Strains

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin
  • Plant Extracts
  • Glucose