Abstract
Oral administration of water fraction of alcoholic extract of leaves of Vinca rosea (fam. apocynaeceae) led to marked lowering of blood glucose level in normal and streptozotocin induced diabetic rats. The hypoglycemic effect of the fraction was comparable with that of tolbutamide.
MeSH terms
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Administration, Oral
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Animals
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Blood Glucose / drug effects*
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Blood Glucose / metabolism
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Diabetes Mellitus, Experimental / drug therapy
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Drug Interactions
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Female
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Glucose / administration & dosage
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Glucose / metabolism
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Glucose Tolerance Test
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Hypoglycemic Agents / pharmacology*
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Insulin / pharmacology
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Male
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Plant Extracts / pharmacology*
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Plants, Medicinal*
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Rats
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Rats, Inbred Strains
Substances
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Blood Glucose
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Hypoglycemic Agents
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Insulin
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Plant Extracts
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Glucose