An efficient and rapid synthetic route to biologically interesting pyranochalcone natural products

Molecules. 2007 Jul 12;12(7):1420-9. doi: 10.3390/12071420.

Abstract

An efficient and concise total synthesis of naturally occurring pyranochalcones was achieved from readily available 2,4-dihydroxyacetophenone and 2,4-dihydroxy-6-methoxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-catalyzed benzopyran formation and aldol reactions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biological Products / chemical synthesis*
  • Biological Products / chemistry*
  • Chalcones / chemical synthesis*
  • Chalcones / chemistry*
  • Chemistry, Organic / methods*
  • Pyrans / chemical synthesis*
  • Pyrans / chemistry*

Substances

  • Biological Products
  • Chalcones
  • Pyrans