Trends in intrapartum fetal death, 1979-2003

Am J Obstet Gynecol. 2008 Jan;198(1):47.e1-7. doi: 10.1016/j.ajog.2007.06.018. Epub 2007 Oct 1.

Abstract

Objectives: This study was undertaken to analyze trends in intrapartum fetal death and rates of perinatal autopsy over a 25-year period in Dublin, Ireland.

Study design: A retrospective multicenter analysis of 508,342 nonanomalous infants 500 g or more, delivering in 3 tertiary-referral university institutions between 1979-2003.

Results: There has been a significant downward trend in the rate of intrapartum fetal death over the past 25 years (P < .0001). Nulliparous labors were statistically more likely to be complicated by an intrapartum fetal demise than parous labors (odds ratio, 1.49; 95% confidence interval [CI], 1.16-1.92; P = .0018). Intrapartum deaths secondary to hypoxia fell significantly over the study period (P < .0001). Infants of multiple gestations were twice as likely to die in labor as singletons (odds ratio, 2.2; 95% CI, 1.22-3.74; P = .0058). Rates of perinatal autopsy fell significantly over the 25 years studied (P < .0001).

Conclusion: There has been a significant fall in rates of intrapartum fetal death. This has primarily resulted from a reduction in deaths attributable to intrapartum hypoxia. Infants of multiple gestations still retain a significantly higher chance of intrapartum death. The fall in uptake rates of perinatal autopsy in recent years is concerning.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Autopsy
  • Cause of Death*
  • Confidence Intervals
  • Female
  • Fetal Death / epidemiology
  • Fetal Mortality / trends*
  • Gestational Age
  • Humans
  • Incidence
  • Ireland / epidemiology
  • Odds Ratio
  • Parity
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy, Multiple
  • Probability
  • Retrospective Studies
  • Risk Factors