Retinal neurostimulator for a multifocal vision prosthesis

IEEE Trans Neural Syst Rehabil Eng. 2007 Sep;15(3):425-34. doi: 10.1109/TNSRE.2007.903958.

Abstract

A neurostimulator application-specific integrated circuit (ASIC) with scalable circuitry that can stimulate 14 channels, has been developed for an epi-retinal vision prosthesis. This ASIC was designed to allow seven identical units to be connected to control up to 98 channels, with the ability to stimulate 14 electrodes simultaneously. The neurostimulator forms part of a vision prosthesis, designed to restore vision to patients who have lost their sight due to retinal diseases such as retinitis pigmentosa and macular degeneration. For charge balance, the neurostimulator was designed to stimulate with current sources and sinks operating together, and with the ability to drive a hexagonal mosaic of electrodes to reduce the electrical crosstalk that occurs when multiple bipolar stimulation sites are active simultaneously. A hexagonal mosaic of electrodes surrounds each stimulation site and has been shown to effectively isolate each site, increasing the ability to inject localized independent charge into multiple regions simultaneously.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electric Stimulation Therapy / instrumentation*
  • Electric Stimulation Therapy / methods
  • Electrodes, Implanted*
  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Prostheses and Implants
  • Retinal Diseases / rehabilitation*
  • Sensory Aids*
  • Signal Processing, Computer-Assisted / instrumentation*
  • Therapy, Computer-Assisted / instrumentation*
  • Therapy, Computer-Assisted / methods
  • Vision Disorders / rehabilitation*