Effect of thought disorders on quality of life in patients with schizophrenia

Prog Neuropsychopharmacol Biol Psychiatry. 2008 Feb 15;32(2):332-5. doi: 10.1016/j.pnpbp.2007.08.033. Epub 2007 Aug 29.

Abstract

Objective: The aim of the present study was to investigate the impact of thought disorder on quality of life in patients with schizophrenia.

Methods: Seventy two patients with schizophrenia and 46 healthy subjects were included in the study. World Health Organization Quality of Life Instrument Short Forum (WHOQOL-BREF) was given to patients and healthy subjects to assess quality of life. Thought and Language Index (TLI) for thought disorders, Positive and Negative Syndrome Scale (PANNS) for symptom and Calgary Depression Scale (CDS) for depressive symptoms were administered to the patients.

Results: The comparison of quality of life between patients and healthy subjects showed a significant difference except environmental domain. There were no significant correlations between thought disorder and quality of life in patients with schizophrenia.

Conclusion: The present study revealed that quality of life was lower in patients with schizophrenia compared to healthy subjects. There was no relation between thought disorders and quality of life in schizophrenia. Patients with schizophrenia were aware of their quality of life perception.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Attitude to Health
  • Awareness
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / epidemiology
  • Comorbidity
  • Control Groups
  • Depressive Disorder / diagnosis
  • Depressive Disorder / epidemiology
  • Female
  • Humans
  • Male
  • Models, Psychological
  • Neuropsychological Tests
  • Psychiatric Status Rating Scales / statistics & numerical data
  • Quality of Life*
  • Schizophrenia / diagnosis*
  • Schizophrenia / epidemiology
  • Schizophrenic Psychology*