Abstract
The phage 21 holin, S(21), forms small membrane holes that depolarize the membrane and is designated as a pinholin, as opposed to large-hole-forming holins, like S(lambda). Pinholins require secreted SAR endolysins, a pairing that may represent an intermediate in the evolution of canonical holin-endolysin systems.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Bacteriolysis / physiology*
-
Cell Membrane / physiology
-
Coliphages / physiology*
-
Endopeptidases / physiology*
-
Escherichia coli / virology*
-
Viral Proteins / physiology*
Substances
-
Viral Proteins
-
Endopeptidases
-
endolysin